Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21 od Jenny A. Klein, Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Angela L. Rachubinski, Joaquin M. Espinosa, Joaquin M. Espinosa, Ella Zeldich, Tarik F. Haydar

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Effects of neonatal neural progenitor cell implantation on adult neuroanatomy and cognition in the Ts65Dn model of Down syndrome. od Angela L Rachubinski, Shannon K Crowley, John R Sladek, Kenneth N Maclean, Kimberly B Bjugstad

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Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling od Congwu Chi, Walter E. Knight, Andrew S. Riching, Zhen Zhang, Roubina Tatavosian, Yonghua Zhuang, Radu Moldovan, Angela L. Rachubinski, Dexiang Gao, Hongyan Xu, Joaquin M. Espinosa, Kunhua Song

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Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome od Micah G. Donovan, Neetha P. Eduthan, Keith P. Smith, Eleanor C. Britton, Hannah R. Lyford, Paula Araya, Ross E. Granrath, Katherine A. Waugh, Belinda Enriquez Estrada, Angela L. Rachubinski, Kelly D. Sullivan, Matthew D. Galbraith, Joaquin M. Espinosa

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Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome od Micah G. Donovan, Angela L. Rachubinski, Keith P. Smith, Paula Araya, Katherine A. Waugh, Belinda Enriquez-Estrada, Eleanor C. Britton, Hannah R. Lyford, Ross E. Granrath, Kyndal A. Schade, Kohl T. Kinning, Neetha Paul Eduthan, Kelly D. Sullivan, Matthew D. Galbraith, Joaquin M. Espinosa

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Neuroimaging abnormalities associated with immunotherapy responsiveness in Down syndrome regression disorder od Jonathan D. Santoro, Mellad M. Khoshnood, Saba Jafarpour, Lina Nguyen, Natalie K. Boyd, Benjamin N. Vogel, Ryan Kammeyer, Lina Patel, Melanie A. Manning, Angela L. Rachubinski, Robyn A. Filipink, Nicole T. Baumer, Stephanie L. Santoro, Catherine Franklin, Benita Tamrazi, Kristen W. Yeom, Gordon Worley, Joaquin M. Espinosa, Michael S. Rafii

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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors od Rani K. Powers, Rachel Culp-Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C. Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona-Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquin M. Espinosa

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Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome od Katherine A. Waugh, Paula Araya, Ahwan Pandey, Kimberly R. Jordan, Keith P. Smith, Ross E. Granrath, Santosh Khanal, Eric T. Butcher, Belinda Enriquez Estrada, Angela L. Rachubinski, Jennifer A. McWilliams, Ross Minter, Tiana Dimasi, Kelley L. Colvin, Dmitry Baturin, Andrew T. Pham, Matthew D. Galbraith, Kyle W. Bartsch, Michael E. Yeager, Christopher C. Porter, Kelly D. Sullivan, Elena W. Hsieh, Joaquin M. Espinosa

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