Sequence dependency of canonical base pair opening in the DNA double helix. Por Viveca Lindahl, Alessandra Villa, Berk Hess

Obter o texto integral

EFFECT OF THE ION TREATMENT ON AN RNA HAIRPIN: MOLECULAR DYNAMICS STUDY Por Elisabeth Catherina Widjajakusuma, Alessandra Villa, Gerhard Stock

Obter o texto integral

Localized Axolemma Deformations Suggest Mechanoporation as Axonal Injury Trigger Por Annaclaudia Montanino, Marzieh Saeedimasine, Alessandra Villa, Svein Kleiven

Obter o texto integral

Elucidating Axonal Injuries Through Molecular Modelling of Myelin Sheaths and Nodes of Ranvier Por Marzieh Saeedimasine, Annaclaudia Montanino, Svein Kleiven, Alessandra Villa

Obter o texto integral

Phage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3. Por Matthias Rinderknecht, Alessandra Villa, Kurt Ballmer-Hofer, Dario Neri, Michael Detmar

Obter o texto integral

Sortase-Mediated Site-Specific Modification of Interleukin‑2 for the Generation of a Tumor-Targeting Acetazolamide–Cytokine Conjugate Por Baptiste Gouyou, Jacopo Millul, Alessandra Villa, Samuele Cazzamalli, Dario Neri, Mattia Matasci

Obter o texto integral

Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility Por Kaoru Nishimura, Elisa Dioguardi, Shunsuke Nishio, Alessandra Villa, Ling Han, Tsukasa Matsuda, Luca Jovine

Obter o texto integral

An Attenuated Targeted-TNF Localizes to Tumors In Vivo and Regains Activity at the Site of Disease Por Sheila Dakhel, Christian Lizak, Mattia Matasci, Jacqueline Mock, Alessandra Villa, Dario Neri, Samuele Cazzamalli

Obter o texto integral

Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo Por Lisa Nadal, Riccardo Corbellari, Alessandra Villa, Tobias Weiss, Michael Weller, Dario Neri, Roberto De Luca

Obter o texto integral

A highly functional synthetic phage display library containing over 40 billion human antibody clones. Por Marcel Weber, Emil Bujak, Alessia Putelli, Alessandra Villa, Mattia Matasci, Laura Gualandi, Teresa Hemmerle, Sarah Wulhfard, Dario Neri

Obter o texto integral

A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Carcinomas Por Roberto De Luca, Baptiste Gouyou, Tiziano Ongaro, Alessandra Villa, Barbara Ziffels, Alessandro Sannino, Gianluca Buttinoni, Simone Galeazzi, Mirko Mazzacuva, Dario Neri

Obter o texto integral

The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study. Por You Xu, Olof Gissberg, Y Vladimir Pabon-Martinez, Jesper Wengel, Karin E Lundin, C I Edvard Smith, Rula Zain, Lennart Nilsson, Alessandra Villa

Obter o texto integral

Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen Por Louis Plüss, Frederik Peissert, Abdullah Elsayed, Giulia Rotta, Jonas Römer, Sheila Dakhel Plaza, Alessandra Villa, Emanuele Puca, Roberto De Luca, Annette Oxenius, Dario Neri

Obter o texto integral

Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies Por Yossa Dwi Hartono, Y. Vladimir Pabon-Martinez, Arzu Uyar, Jesper Wengel, Karin E. Lundin, Rula Zain, C. I. Edvard Smith, Lennart Nilsson, Alessandra Villa

Obter o texto integral

Therapeutic Evaluation of Antibody-Based Targeted Delivery of Interleukin 9 in Experimental Pulmonary Hypertension Por Baptiste Gouyou, Katja Grün, Anne Kerschenmeyer, Alessandra Villa, Mattia Matasci, Andrea Schrepper, Alexander Pfeil, Laura Bäz, Christian Jung, P. Christian Schulze, Dario Neri, Marcus Franz

Obter o texto integral

Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer Por Chiara Francavilla, Michela Lupia, Kalliopi Tsafou, Alessandra Villa, Katarzyna Kowalczyk, Rosa Rakownikow Jersie-Christensen, Giovanni Bertalot, Stefano Confalonieri, Søren Brunak, Lars J. Jensen, Ugo Cavallaro, Jesper V. Olsen

Obter o texto integral

L1CAM promotes ovarian cancer stemness and tumor initiation via FGFR1/SRC/STAT3 signaling Por Marco Giordano, Alessandra Decio, Chiara Battistini, Micol Baronio, Fabrizio Bianchi, Alessandra Villa, Giovanni Bertalot, Stefano Freddi, Michela Lupia, Maria Giovanna Jodice, Paolo Ubezio, Nicoletta Colombo, Raffaella Giavazzi, Ugo Cavallaro

Obter o texto integral

Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties Por Abdullah Elsayed, Christian Pellegrino, Louis Plüss, Frederik Peissert, Ramon Benz, Franziska Ulrich, Gudrun Thorhallsdottir, Sheila Dakhel Plaza, Alessandra Villa, Jacqueline Mock, Emanuele Puca, Roberto De Luca, Markus G. Manz, Cornelia Halin, Dario Neri

Obter o texto integral